GO:0000176 cellular_component nuclear exosome (RNase complex)
| PAG Title | GO:0000176 cellular_component nuclear exosome (RNase complex) |
| PAG ID | TAX013293 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 4,112 |
| Information Content | Rich |
| Other IDs | GO:0000176 |
| Base PAG ID | TAX013293 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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